A single solution for copy number estimation from arrays, WES, WGS, shallow, and targeted sequencing!
Researchers around the world rely on Nexus Copy Number for accurate copy number calling. It is a highly robust, intuitive, and multi-platform software for both copy number calling and downstream statistical analyses. A key feature of Nexus Copy Number is its ability to derive high quality copy number calls from many flavors of NGS (whole exome, whole genome, shallow, targeted panel, and normal depth of coverage sequencing).
Nexus Copy Number 10.0 continues to provide an extensive list of statistical and visualization tools to perform large cohort studies: comparisons to identify statistically significant differences between subgroups, identification of cooperating events, clustering, gene enrichment, and more. With integration of sequence variant analysis along with copy number and AOH, Nexus Copy Number is a one-stop solution for data from a wide range of NGS and array technologies. Other features in version 10.0 include export of the distance matrix for clustering, user-specified event colors, and plotting of BAF (B-allele frequency) for the BAM ngCGH (matched) algorithm.
BioDiscovery’s platform-independent software packages provide a complete spectrum of data analysis solutions for gene expression (RNASeq, mRNA, miRNA) and copy number and sequence variation from microarray and NGS (WES, WGS, targeted panels) technologies. Nexus Copy Number is a user-friendly and robust software solution with specialized cancer specific tools and algorithms and the capability to handle large volumes of data. With its ability to handle virtually any genome and integrate data from different modalities (gene expression, copy number, sequence variation), it offers a more complete picture of the genomic landscape.