This webinar is geared towards researchers performing copy number and allelic event analysis of the Autism Spectrum Disorders. It is also applicable to anyone interested in a more efficient system to extract meaningful results from genomic aberration data.
Genetic studies of various diseases and disorders requires researchers to sift through vast amounts of accumulated data from diverse sources in order to identify key factors that play a role in these disorders. Having the right tools makes all the difference in processing the data efficiently to accelerate discovery. The Autism Genetic Resource Exchange, a program of Autism Speaks, has a large collection of genotype and phenotype data for individuals with ASD and their family members. This data has been available to AGRE members but now AGRE is providing the copy number and allelic event array data via BioDiscovery Nexus DB so that researchers can quickly and efficiently analyze the data enabling faster discoveries. In this presentation we will show how to access and efficiently explore the AGRE data using BioDiscovery Nexus Copy Number and Nexus DB. The system integrates the information from the AGRE consortium with other databases, such as DGV, UCSC, etc. into a single user interface and allows querying of the AGRE data against a specific case or a population of samples to aid the researcher in making the best interpretation of the observed data. An example workflow using different array platforms will be presented.