BioDiscovery Resources

BioDiscovery White Papers

Take a closer, more in-depth look at relevant industry topics and applications.

Comparison of CNV Detection Between Whole-Exome Sequencing and Microarray Platforms in Cancer Samples

Learn more about the various methods that have been proposed to detect CNVs from NGS data in tumor-normal matched paired colon adenocarcinoma samples.

ACMG Standards and Guidelines Implementation in NxClinical

Download our new whitepaper on ACMG Standards and Guidelines Implementation in NxClinical.

Analyzing NGS Data For Copy Number Events

Next-generation sequencing (NGS) is mainly used to obtain sequence variants (SNVs). However, getting copy number variants (CNVs) from NGS has gained momentum in both research and clinical applications.

Addressing Aneuploidy and Nonaberrant Cell Admixture in Tumor Samples for Copy Number Variation (CNV) and Loss of Heterozygosity (LOH) Analysis

Explore the use of LogR and B-allele frequency values from SNP arrays to interpret the underlying biology of tumor samples, along with limitations of this approach.